TGFB1 and cancer: We note that, in SW480 cells, the greatest effect on adhesion in the cell lines was caused by treatment with the Hsp90 inhibitor novobiocin, which both alone and in combination with TGF-β1 and Hsp90β, decreased the level of adhesion in both cell lines, suggesting that it is Hsp90β and not TGF-β1 which plays the more important role in regulating adhesion in these cancer cells.