The ATA/ACC and ATA/ATA genotypes occur at a frequency of 24.5% and 22.1% respectively in the 1000 genomes South Asian (SAS) participants, so these probabilities multiplied by the probabilities of the FBLIM1 mutations found in the two families result in combined genotype frequencies that are more consistent with the incidence of CRMO. The gene discussed is FBLIM1; the disease is chronic recurrent multifocal osteomyelitis.