Results showed that all five CRC cell lines (HT-29, SW620, HCT-15, HCT116, and COLO205) had higher WDR5 expression level than the normal intestinal epithelial cell line (FHC) at both the mRNA level (Figure 1a; P<0.05) and the protein level (Figure 1b). Here, WDR5 is linked to colorectal carcinoma.