Moreover, it was reported that missense mutations in ZNF407 affect tumor progression, as evidenced by whole-genome sequencing of gastrointestinal stromal tumors.28 Moreover, our functional studies of ZNF407 showed that ZNF407 functioned as a promotive factor in CRC metastasis and accelerated cell proliferation slightly (Supplementary Figure S3). Here, ZNF407 is linked to neoplasm.