When we analyzed a series of 59 patient samples of colon cancer tissues at various stages using by ImageJ (http://openwetware.org/wiki/Sean_Lauber:ImageJ-Threshold_Analysis), CST1 expression was higher in all stages of CRC tissues (14–26%) than in normal tissues (~5%), particularly in tumor stages I, III, and IV. Here, CST1 is linked to colonic neoplasm.