Here, we assessed whether the variant of BST-2 in cancer cells is critical for BST-2:BST-2 interactions that mediate cell to cell and/or cell to matrix adhesion.3 As expected, OE-BST-2D but not OE-BST-2M significantly increases adhesion of cancer cells to collagen (Figure 2d) and fibronectin (Figure 2e), despite comparable expression (Figure 2b). The gene discussed is BST2; the disease is cancer.