CD8A and type 1 diabetes mellitus: Within memory CD8+ T cells, IGRP α2, the dominant TCR α-chain shared by patients T1D-1 and T1D-2, was detected in none of 11 control children as compared to 2 (20%) of 10 autoantibody positive children and 3 (43%) of 7 recent onset type 1 diabetes patients (P = 0.042 controls vs patients).