CNR1 and neoplasm: However, when the steady-state levels of mature transcripts were compared, we found E1A-cB1-3′-UTR mRNA to be significantly lower in HPDE cells as compared to E1A-WT-3′-UTR mRNA as well as reduced with respect to E1A- cB1-3′-UTR mRNA in tumour cells (Fig. 2b).