CORO1A and infection: Regarding the role of coronin 1A in osteoclast precursor cells, i.e., in monocyte/macrophage-lineage cells, it has been shown that the inflammatory stimulation-induced coronin 1A phosphorylation triggers cellular switching from phagocytosis to micropinocytosis, which enables efficient uptake and degradation of large amounts of infectious materials60, 61, suggesting that coronin 1A is important for host defense against infection.