CXCL8 and cholestasis: Patients with AILD and higher serum IL-8 levels tended to have higher levels of total bilirubin, AST, alkaline phosphatase, and ESR and lower level of serum albumin, indicating lower liver synthetic function (albumin), higher grades of cytolysis (AST), and cholestasis (alkaline phosphatase), as well as higher grade of systemic inflammation (ESR).