We too found that LAMP2 surface localization was significantly enhanced in the regions attributed with ‘very low’ (necrotic zone) and ‘low pH’ (pseudo-palisading and cellular tumor zones) in the glioblastoma patient samples (Figure 1B) [US Biomax glioblastoma tissue arrays containing 63 distinct patient samples were processed for this analysis; here, ‘R’ denotes the colocalization coefficient between wheat germ agglutinin (binds to cell surface marker) and LAMP2 surface localization]. The gene discussed is LAMP2; the disease is neoplasm.