Aside from SorLA, Lrp1 (Kang et al., 1997), Lrp1b (Shang et al., 2015), Lrp2 (Wang et al., 2011), Lrp4 (Vargas et al., 2010), Lrp6 (De Ferrari et al., 2007) and Apoer2 (Ma et al., 2002) have been associated with AD risk. Here, SORL1 is linked to Alzheimer disease.