CASP3 and urinary bladder carcinoma: As seen in Fig. 2B, the percentages of apoptotic caspase 3/7 positive cells for 5637 cells were 51.53, 47.42, 54.46, and 31.66% in the AUY922, ganetespib, SNX2112, and AT13387 groups, respectively, whereas the percentages of caspase 3/7 positive cells for the control SV-HUC cells were 16.29, 18.32, 18.60, and 11.17% in the AUY922, ganetespib, SNX2112, and AT13387 groups, respectively, thus showing nearly threefold differences in percentages of caspase 3/7 positive cells between the bladder cancer cells and the control cells (p < 0.05).