Additional variables significantly associated with HF admission in univariate analysis included LVEF (p <0.001), NYHA functional class III (p 0.01), systolic blood pressure (p < 0.001), diastolic blood pressure (p 0.025), history of ischemic heart disease (p 0.021), dementia (p 0.018) sodium level (p 0.018) and angiotensin converting enzyme inhibitors-angiotensin receptor blockers (ACEI-ARBs) use (p 0.008). This evidence concerns the gene ACE and hydrops fetalis.