We found that FTY720 induces similar effects in AB1 mouse MM cells, as compared to human MM cells, including SET displacement from PP2A complex (Additional file 6: Figure S6A), reduction of p-AKT (Ser473) and Bcl-2, and induction of caspase-3 cleavage (Additional file 6: Figure S6B). This evidence concerns the gene CASP3 and Miyoshi myopathy.