BAG3 and familial dilated cardiomyopathy: This locus was the second one identified in our earlier GWAS.(3) rs2234962 (BAG3,c.451T>C, p.Cys151Arg, MAF = 0.19) confers a reduced risk of DCM (OR = 0.62 (0.57–0.68), P = 1.7x10-25).