Moreover, our results are the first to raise the possibility that 43 SNPs in the RORA gene and 6 SNPs in the RORB gene may contribute to the susceptibility for MetS, especially RORA (rs17237367, rs58469372, rs12591650, rs12594188, rs17270446, rs11630062, rs8029848, rs8034880, rs72752802) and RORB rs972902. The gene discussed is RORB; the disease is metabolic syndrome.