IL6 and oral lichen planus: IL6, mainly produced by antigen-presenting cells (APCs),[27] involved in OLP development may include T-cell growth and differentiation, apoptosis of keratinocytes from the basal layer and epithelial proliferation, resulting in hyperplasia.[28,29] Besides, there was evidence that the level of IL6 was elevated in saliva and serum in OLP patients, especially in the erosive form of OLP.[29,30] The results of our meta-analysis failed to find an association between IL6-174G/C and OLP susceptibility in any genetic models.