The univariate analysis showed that the raised AFP (P = 0.003) and hs-CRP levels (P = 0.001), larger tumor size (P = 0.019), incomplete encapsulation of the tumor (P = 0.030), the presence of MVI (P = 0.006), and double positive staining for CK19 and CK7 (P < 0.001) to be significant predictors for OS. This evidence concerns the gene CRP and neoplasm.