In addition, it also has close relationship with the origination and progression of multiple tumors, affecting the development of tumors through influencing cells’ ability of adhesion and activity, the formation of thrombi, the expression of tumor-specific antigens, and the proliferation of tumor cells.[36–38] Several studies have shown an association between IL-6 gene polymorphisms and the risk of prostate cancer, but the results are inconclusive. This evidence concerns the gene IL6 and Familial prostate cancer.