Our initial quantitative real‐time RT‐PCR (qPCR) analysis included 13 known cardiac‐specific or cardiac‐related lncRNAs: SRA, DIO3OS, SAF, NESPAS, MIAT, NRON, CARL, HCG22, FENDRR, MHRT, aHIF, ZFAS1 and CDR1AS. As illustrated in Figure 1A, of 13 lncRNAs tested, only two, NRON and myosin heavy–chain‐associated RNA transcripts (MHRT), demonstrated significant differences in plasma samples between HF and non‐HF. Here, HCG22 is linked to hydrops fetalis.