Interestingly, we found that TBL1XR1 expression was positively correlated with the Cyclin D1 (P = 0.035, Fig. 4A–C) and c-Myc levels (P = 0.047, Fig. 4D–F) in CRC tissues, both are well-known β-catenin-regulated proteins. This evidence concerns the gene MYC and colorectal carcinoma.