However, including CRP as a mediator in the multivariable model did change the results, especially the association with CHD incidence was attenuated after inclusion of CRP for the DASH score (HR 0.84; 0.64, 1.10 and after inclusion of CRP HR 0.96; 0.83, 1.28), while the association with stroke incidence became stronger after inclusion of CRP for the AHEI-2010 (HR 0.66; 0.44, 0.99 and after adjusting HR 0.56; 0.34, 0.93). The gene discussed is CRP; the disease is Stroke.