In multivariate analysis, factors associated with hypertriglyceridemia were increased age (OR: 1.28, 95% CI: 1.02–1.61; p = 0.032), nadir CD4 cell count > 350 cells/mm3 (OR: 7.56, 95% CI: 1.68–34.03; p = 0.008), and presence of lipodystrophy (OR: 3.48, 95% CI: 1.01–12.01; p = 0.048). This evidence concerns the gene CD4 and lipodystrophy.