KLK3 and posterior cortical atrophy: At a PCA3 cutoff of 23.5, the sensitivity of the PCa3 score was 97.0% and the specificity was 41.6% whereas a cutoff of 214.3 would have a positive predicted value of 50%, indicating that patients with a PCA3 score over this cutoff value would have a high chance of being diagnosed with PCa, especially when taking the PSA range into consideration.