In contrast, there were more factors notably altered in serum; among these, IL‐2, IL‐6, IL‐10, IL‐15, IL‐17, G‐CSF, GM‐CSF, bFGF, VEGF, MIP‐1α, MCP‐1, and IFN‐γ levels were strongly increased in ALS patients. Here, CSF3 is linked to amyotrophic lateral sclerosis.