In T2–T4 tumours, none of the established clinicopathological factors remained significant, but RBM3 was borderline prognostic in both univariable (HR 2.01, 95% CI 0.95–4.23) and multivariable analysis (HR 2.22, 95% CI 0.94–5.28). Here, RBM3 is linked to neoplasm.