The laboratory examination, including determining the blood glucose of hypoglycemia, determining simultaneously the serum insulin and the C-peptide, and carrying out starvation test, aims at confirming the existence of hypoglycemia and that it is caused by the improper secretion of endogenous insulin, that is, when the plasma glucose concentration ≤2.80 mmol/L, the insulin concentration >25 mIU/L, the Insulin Release Index (IRI) >0.3. Here, INS is linked to Hypoglycemia.