The proportions of CD4+CD25+Foxp3+ Tregs among PGF patients, GGF patients and HD were comparable (Fig. 3, 4.5 vs. 2.8 vs. 3.3%, P > 0.05), and the percentages of CD4+CD25+CD127−/dim Tregs showed no significant difference among patients with PGF, GGF and HD (Additional file 1: Figure S1). This evidence concerns the gene IL7R and Huntington disease.