To investigate the contributions of the causative genes for ALS in Chinese patients, we reviewed the previously reported mutation frequencies of common causative genes, including SOD1, TARDBP, FUS, ANG, VCP, SQSTM1, PFN1, TBK1, CHCHD10 and C9orf72, in Chinese populations. This evidence concerns the gene TBK1 and amyotrophic lateral sclerosis.