To investigate the contributions of the causative genes for ALS in Chinese patients, we reviewed the previously reported mutation frequencies of common causative genes, including SOD1, TARDBP, FUS, ANG, VCP, SQSTM1, PFN1, TBK1, CHCHD10 and C9orf72, in Chinese populations. The gene discussed is SOD1; the disease is amyotrophic lateral sclerosis.