Among these is resistin, whose circulating and/or tissue expression levels have been associated with atherosclerosis and related clinical phenotypes, including major adverse cardiovascular events (MACE)6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21. This evidence concerns the gene RETN and atherosclerosis.