Although, no significant serum viremia or tissue viral load was observed in NRG-MIS mice over the course of infection (Fig. 6b), serum viremia in NRG-HIS mice increased rapidly over time following infection and plateaued at low-levels 3 to 4 days post infection, which was distinct from the serum viremia profile of WT and stat1loxP/loxP/Vav-cre mice (Fig. 6c). Here, VAV1 is linked to infection.