In silico target prediction of selected miRNAs, such as miR-31 and miR-4417 which are upregulated in tumor samples [57, 58], revealed a set of potential target mRNAs including Flavin containing monooxigenase 4 (FMO4), cyclin dependent kinase inhibitor 2B (CDKN2B), and prostaglandin D2 receptor (PTGDR), whose expression pattern changed oppositely  according to our (Human Transcriptome Array 2.0 microarray) results﻿. The gene discussed is CDKN2B; the disease is neoplasm.