Heterogenic, significantly (p < 0.05) increased nuclear Cyclin D1 expression (representative scoring values: +2; +3) was detected in epithelial compartment of adenomas (Q score: 80.00 ± 17.88; Fig. 8b) and CRCs (Q score: 129.50 ± 45.85; Fig. 8c). This evidence concerns the gene CCND1 and adenoma.