Serum levels of sTNF-R1 and sTNF-R2 resulted higher in both active BD (p = 0.002 and p = 0.002, respectively) and inactive BD (p = 0.0101 and p = 0.002, respectively) subgroup than HC, while Chitinase3-like1 (p = 0.042) and gp130/sIL-6Rb (p = 0.008) serum levels were significantly higher in inactive BD as well as IL-26 (p = 0.002) in active BD than HC (Figure 2). This evidence concerns the gene IL6ST and Behcet disease.