TNF and Behcet disease: Moreover, 27 serum samples were obtained from HLA-B51-positive BD patients (50%) and at the time of serum collection patients were receiving the following treatments: TNF inhibitors 21/54, DMARDs combined with corticosteroids 14/54, DMARDs alone 10/54, corticosteroids 3/54, anti-IL-1 agents 3/54, and three patients were no treated.