We found an increase in the percentage of an analogous CXCR3+CCR6+ expressing Tfh population in the smB− group compared to controls (9.25 vs. 4.36%; p < 0.05) and to smB+ CVID patients (9.25 vs. 3.81%; p < 0.05), but not between smB+ CVID patients and controls (Figures 3A,J). The gene discussed is CXCR3; the disease is common variable immunodeficiency.