No differences were found between controls and smB− or smB+ CVID patients in the distribution of naïve (CCR7+CD45RA+), central (CCR7+CD45RA−), and effector (CCR7−CD45RA−) memory subpopulations on circulating CD4+CXCR5+ cells (Table S1 in Supplementary Material). Here, CXCR5 is linked to common variable immunodeficiency.