NFKB1 and familial pancreatic carcinoma: By analyzing GPR87 mRNA expression and NF-κB-regulated gene signatures from published pancreatic cancer patient profiles (TCGA datasets), we found that GPR87 expression was positively correlated with NF-κB signaling gene signatures (Fig. 5a and Additional file 6: Figure S4), raising the possibility that GPR87 upregulation may activate NF-κB signaling pathway in pancreatic cancer.