GLS and cancer: By comparing the lists of top-ranking cancer-related target genes, we were able to identify seven promising cancer-related genes that may be targets of the hsa_circRNA_100395/miR-141-3p/ miR-200a-3p axis in PTC (in order of descending rank): E2F3, GLS, CCND2, PTEN, CCNG1, CDC25B, and ZFPM2 (Tables 4 and 5).