This upregulation of miR-141-3p and/or miR-200a-3p may have effects on several cancer-related target genes that have been previously associated with these two miRNAs, including E2F3, GLS, CCND2, PTEN, CCNG1, CDC25B, and ZFPM2 (Tables 4 and 5). This evidence concerns the gene PTEN and cancer.