Parathyroid tumours (Figures 3b–d), which were ~1 mm in length (Supplementary Figure 2) and had a heterogenous architecture, developed in Cdc73+/−, and Cdc73+/L/PTH-Cre and Cdc73L/L/PTH-Cre mice, and these demonstrated abnormalities that included glandular enlargement, nuclear pleomorphism, and septation (Figures 3b–d), which are features often observed in PCs and APAs. Here, PTH is linked to tumor of parathyroid gland.