CDC73 and tumor of uterus: In summary, we have established a conventional Cdc73+/− mouse, in which males and females develop PAs and APAs, and females develop uterine tumours; thus this Cdc73+/− mouse model is representative of the human HPT-JT syndrome.13, 14, 15 Moreover, we have developed parathyroid-specific Cdc73 knockout mouse models, which develop APAs and PAs.