Parathyroid tumours (Figures 3b–d), which were ~1 mm in length (Supplementary Figure 2) and had a heterogenous architecture, developed in Cdc73+/−, and Cdc73+/L/PTH-Cre and Cdc73L/L/PTH-Cre mice, and these demonstrated abnormalities that included glandular enlargement, nuclear pleomorphism, and septation (Figures 3b–d), which are features often observed in PCs and APAs. The gene discussed is CDC73; the disease is tumor of parathyroid gland.