The parathyroid tumours developing in the Cdc73+/− and Cdc73+/L/PTH-Cre mice had significantly higher daily proliferation rates, by three- to fourfold, while that of Cdc73L/L/PTH-Cre mice was ~9-fold higher, when compared to those of parathyroid glands in wild-type mice Cdc73+/+ and Cdc73+/+/PTH-Cre mice (Table 2, P<0.0001). This evidence concerns the gene PTH and tumor of parathyroid gland.