PTH and tumor of parathyroid gland: Parathyroid tumours were found in >65% of Cdc73+/− mice (n=15/22) but in none of 16 Cdc73+/+ littermates (P<0.0001, two-tailed Fisher’s exact test, Table 1), between 9 and 18 months of age; and in ⩾50% of ⩾18-month-old Cdc73+/L/PTH-Cre (n=7/12) and Cdc73L/L/PTH-Cre (n=6/12) mice, but not in any of 19 Cdc73+/+/PTH-Cre littermates (P<0.005).