Targeted cancer therapies are effective for the treatment of certain oncogene-driven solid tumors, including non-small cell lung cancers (NSCLCs) with activating genetic alterations in EGFR (epidermal growth factor receptor), ALK (anaplastic lymphoma kinase), BRAF, and ROS1 kinases1, 2, 3. The gene discussed is EGFR; the disease is non-small cell lung carcinoma.