Currently, there are ongoing trials recruiting patients evaluating the use of mTOR inhibitors (i.e., mTORC1/2 inhibitor AZD2014 or the oral AKT inhibitor AZD5363 for recurrent endometrial, NCT02208375; ovarian cancer and a phase I trial of the combination of AZD2014 and weekly paclitaxel, NCT02193633) and in view of this new data, this question might be clarified. This evidence concerns the gene AKT1 and ovarian carcinoma.