BCL2 and Familial prostate cancer: A study has shown that the inhibition of cell viability and the induction of apoptosis in PC-3 and LNCaP cells by ursolic acid were associated with downregulation of the B-Cell Lymphoma 2 (BCL-2) protein [23], a member of the protein cell family that controls apoptosis to prevent prostate cancer progression [27, 28].