The effect of lung cancer on ln (CRP) remained significant (2.18 vs 1.49) after adjusting for BMI (p = 0.05), age (n.s.), eGFR (n.s.), smoking status at the time of referral (p = 0.02), sex (n.s.), the presence of active malignant disease (p < 0.01), and the presence of heart disease (p = 0.03). The gene discussed is CRP; the disease is lung cancer.