CD8A and malaria: To illustrate this point it is useful to consider the potential correlates of protection to the pre-erythrocytic stage of malaria because if, as previously demonstrated in both mouse [30] and humans [31] the induction of CD8+ T effector memory cells are essential for pre-erythrocytic protection against malaria, then the impact of cryopreservation may not be important as the flow cytometry data presented here indicates that this population is less likely to be affected.