ITGAM and primary biliary cholangitis: As shown in Supplementary Fig. 1, HD(F) had similar levels of circulating CD33+ (HD(F); 79.6 ± 3.7 vs PBC;77.0 ± 2.9), CD33+CD11b+ (HD(F); 76.9 ± 3.5 vs PBC;74.3 ± 3.0) and CD33+CD11b+HLA-DR−/low cells (HD(F); 73.3 ± 3.4 vs PBC;71.4 ± 3.1), compared to PBC patients (Supplementary Figs. 1A–C).