Currently, it is estimated that eight percent of all cancers have mutations in the BRAF gene, and they are present in a wide range of malignant tumours including ~50% of melanomas [5], ~40% of papillary thyroid cancer (PTC) [6], ~30% of serous ovarian cancer [6,7,8,9], ~10% of colorectal cancers (CRC) [10], and ~2%–3% of lung cancers [7,11]. The gene discussed is BRAF; the disease is colorectal cancer.