Two women in this group had two pathogenic mutations each, in two different genes: one had pathogenic mutations in CHEK2 and RAD51C, and the other had pathogenic mutations in ATM and PALB2. Pathogenic mutations were observed in several genes with well-established ovarian cancer risk: MSH6, NBN, RAD51C, and one mutation in BRCA1 that was previously undetected due to limited testing. Here, MSH6 is linked to ovarian cancer.