Overexpression of isoforms 1A3, 3A2 and 7A1 in ovarian cancer appear to be a more consistent finding.18 ALDH7A1 overexpression is reported to contribute to metastasis in prostate cancer.19 Overexpression of ALDH3A1 has also been identified in prostate cancer and hepatocellular carcinoma. The gene discussed is ALDH7A1; the disease is Familial prostate cancer.