Treating the subjects as random effects and the number of assessments as repeated measurements, we generated an initial GEE model (binomial, link function logit) with the dependent variable as the presence or not of delirium (as defined with the DRS-R98) at any assessment and as independent variables the levels of BDNF, APACHE II, MoCA scores, age, gender, and previous history of dementia. This evidence concerns the gene BDNF and delirium.