The lack of association with the transfusion-dependent β-thalassemia major and association with the Hb E/β-thalassemia cases [31] and beta-thalassemia carriers [28] suggests that rs4671393, rs7557939, and rs11886868 are HbF enhancer SNPs in β-thalassemia intermedia. Here, GSTM1 is linked to Beta-thalassemia.