MYC and cancer: Multiple studies in mouse models of cancer demonstrated Omomyc's therapeutic impact in different types of cancer, independently of their driving mutation or tissue of origin, pointing to the key role of Myc in tumorigenesis downstream of the diverse oncogenic lesions (Soucek et al., 2004, 2008, 2013; Sodir et al., 2011; Annibali et al., 2014; Galardi et al., 2016).