IL4 and myeloid sarcoma: The fact that specific NKT cells prevalence and function is restored in MS patients in remission after IFN-β treatment (12); that oral corticosteroids induce a Th2 bias in the cytokine profile of these cells (20); and that 1,25(OH)D3 vitamin induce protection from EAE in mice dependent of NKT cell-derived IL-4 (21) suggests that NKT cells might exert immunoregulatory more than detrimental effects in MS.